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New Strategy Cracks Staph Bacterium's "Golden Armor," Making It Vulnerable To Treatment

Categorie : Cholesterol
Researchers have exploited a structural vulnerability in the "superbug" Staphylococcus aureus that in laboratory experiments and a mouse study opened the bacterium to treatment with an anti-cholesterol medication. This follows the 2005 discovery that a pigment provides a "golden armor" that enables ...

read more Researchers have exploited a structural vulnerability in the read more Fri Feb 2008 Fri Feb 2008

Percentage Of Insured Adults Using Prescription Drugs Increased, Study Finds

Categorie : Cholesterol
The percentage of U.S. adults taking prescription drugs to treat health conditions such as high cholesterol, diabetes, depression and hypertension increased significantly between 2000 and 2006, according to a study released on Tuesday by Express Scripts, USA Today reports. ...

read more The percentage of U.S. adults taking prescription drugs to treat health conditions such as high cholesterol, diabetes, depression and hypertension increased significantly between 2000 and 2006, according to a study released on Tuesday by Express Scripts, USA Today reports. read more Fri Feb 2008 Fri Feb 2008

Children May Have Cholesterol Problems, Too

Categorie : Cholesterol
High cholesterol levels are not just found in adults. Children may have high cholesterol, too, even without being overweight. Over years, cholesterol overload has similar hazards as in adults -- clogged arteries and injury to the heart. ...

read more High cholesterol levels are not just found in adults. Children may have high cholesterol, too, even without being overweight. Over years, cholesterol overload has similar hazards as in adults -- clogged arteries and injury to the heart. read more Tue Feb 2008 Tue Feb 2008

Prions Link Cholesterol To Neurodegeneration

Categorie : Cholesterol
Prion infection of neurons increases the free cholesterol content in cell membranes. A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for chole ...

read more Prion infection of neurons increases the free cholesterol content in cell membranes. A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for chole read more Tue Feb 2008 Tue Feb 2008

House Subcommittee Investigates Advertisements For Cholesterol Medication Lipitor

Categorie : Cholesterol
The House Energy and Commerce Subcommittee on Oversight and Investigations on Thursday sent letters to advertising agencies believed to be involved with a television ad campaign for the cholesterol medication Lipitor, manufactured by Pfizer, that features Robert Jarvik, inventor of the first artific ...

read more The House Energy and Commerce Subcommittee on Oversight and Investigations on Thursday sent letters to advertising agencies believed to be involved with a television ad campaign for the cholesterol medication Lipitor, manufactured by Pfizer, that features Robert Jarvik, inventor of the first artific read more Tue Feb 2008 Tue Feb 2008

Scientists Reveal A New Target To Fight Bad Cholesterol

Categorie : Cholesterol
Scientists have uncovered a new region in the genome that is responsible for the body's ability to regulate bad cholesterol which is linked to heart attack and stroke. Their findings are published in the Lancet. The researchers found three genetic variations in the same region on chromosome 1 which ...

read more Scientists have uncovered a new region in the genome that is responsible for the body's ability to regulate bad cholesterol which is linked to heart attack and stroke. Their findings are published in the Lancet. The researchers found three genetic variations in the same region on chromosome 1 which  read more Tue Feb 2008 Tue Feb 2008

Making Statins Even Better

Categorie : Cholesterol
Statin drugs are helping many people lower their cholesterol, but a new study in the February Journal of Lipid Research reveals that statins actually increase the production of another protein that limits their benefit.Proprotein convertase type 9 (PCSK9) has recently gained attention as a key regul ...

read more Statin drugs are helping many people lower their cholesterol, but a new study in the February Journal of Lipid Research reveals that statins actually increase the production of another protein that limits their benefit.Proprotein convertase type 9 (PCSK9) has recently gained attention as a key regul read more Tue Feb 2008 Tue Feb 2008

Diabetes, Cholesterol, Anti-obesity Drugs Top Spending

Categorie : Cholesterol
U.S. adult consumers spent nearly $36 billion for prescription drugs to lower blood sugar, reduce cholesterol, or help with other metabolic problems in 2005, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. The four other classes of drugs that topped spen ...

read more U.S. adult consumers spent nearly $36 billion for prescription drugs to lower blood sugar, reduce cholesterol, or help with other metabolic problems in 2005, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. The four other classes of drugs that topped spen read more Tue Feb 2008 Tue Feb 2008

Common Disturbance In Metabolism Of Fat Caused By Disrupted Genetic Regulation

Categorie : Cholesterol
The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks. Uppsala University scientists have now developed a pioneering method and can show for the first time what genes are regulated by the gene USF1, which is known to cause the dis ...

read more The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks. Uppsala University scientists have now developed a pioneering method and can show for the first time what genes are regulated by the gene USF1, which is known to cause the dis read more Tue Feb 2008 Tue Feb 2008

PreMD Announces FDA Decision On POC Skin Cholesterol Test

Categorie : Cholesterol
Predictive medicine company PreMD Inc. (TSX: PMD; Amex: PME) announced that it has received a non-substantially equivalent (NSE) letter from the U.S. Food and Drug Administration (FDA) regarding the 510(k) submission for an expanded regulatory claim on its point-of-care (POC) skin cholesterol test. ...

read more Predictive medicine company PreMD Inc. (TSX: PMD; Amex: PME) announced that it has received a non-substantially equivalent (NSE) letter from the U.S. Food and Drug Administration (FDA) regarding the 510(k) submission for an expanded regulatory claim on its point-of-care (POC) skin cholesterol test.  read more Thu Jan 2008 Thu Jan 2008

Cleveland Clinic To Lead First Head-to-Head Comparison Of The Two Most Potent Statins

Categorie : Cholesterol
Cleveland Clinic researchers will coordinate the first head-to-head comparison of the two most powerful statin medications. The trial intends to begin enrollment as early as next week. Statins are the world's most commonly prescribed drugs and widely used to treat patients with elevated cholesterol ...

read more Cleveland Clinic researchers will coordinate the first head-to-head comparison of the two most powerful statin medications. The trial intends to begin enrollment as early as next week. Statins are the world's most commonly prescribed drugs and widely used to treat patients with elevated cholesterol  read more Thu Jan 2008 Thu Jan 2008

Merck, Schering-Plough Offer Explanation For Delay In Release Of Vytorin Study Results

Categorie : Cholesterol
Merck and Schering-Plough recently offered a detailed explanation of their decision to delay the release of the results of a study of the cholesterol medication Vytorin, the Wall Street Journal reports. The study, called Enhance, ended in April 2006, but the companies did not release the results un ...

read more Merck and Schering-Plough recently offered a detailed explanation of their decision to delay the release of the results of a study of the cholesterol medication Vytorin, the Wall Street Journal reports.  The study, called Enhance, ended in April 2006, but the companies did not release the results un read more Thu Jan 2008 Thu Jan 2008

FDA Issues Early Communication About An Ongoing Review Of Vytorin

Categorie : Cholesterol
The U.S. Food and Drug Administration issued an Early Communication regarding the agency's ongoing review of Vytorin based on preliminary results from a recently completed study - the Effect of Combination Ezetimibe and High-Dose Simvastatin vs. Simvastatin Alone on the Atherosclerotic Process in Pa ...

read more The U.S. Food and Drug Administration issued an Early Communication regarding the agency's ongoing review of Vytorin based on preliminary results from a recently completed study - the Effect of Combination Ezetimibe and High-Dose Simvastatin vs. Simvastatin Alone on the Atherosclerotic Process in Pa read more Thu Jan 2008 Thu Jan 2008

Recent Studies Of Vytorin, Avandia Prompt Debate About FDA Approval Process For New Medications

Categorie : Cholesterol
Recent studies that raised questions about the benefits of the cholesterol medication Vytorin, manufactured by Merck and Schering-Plough, and the ...

read more Recent studies that raised questions about the benefits of the cholesterol medication Vytorin, manufactured by Merck and Schering-Plough, and the  read more Thu Jan 2008 Thu Jan 2008

Seasonal Weight Changes Linked To Metabolic Syndrome

Categorie : Cholesterol
Seasonal changes in weight increase the risk for metabolic syndrome, a group of scientists from National Public Health Institute, Helsinki, Finland, reports in a study published in the January 23 issue of the online, open-access journal PLoS ONE.This finding was based on analysis of 8,028 individual ...

read more Seasonal changes in weight increase the risk for metabolic syndrome, a group of scientists from National Public Health Institute, Helsinki, Finland, reports in a study published in the January 23 issue of the online, open-access journal PLoS ONE.This finding was based on analysis of 8,028 individual read more Thu Jan 2008 Thu Jan 2008

Study Prompts Patients To Question Whether They Should Continue Use Of Vytorin

Categorie : Cholesterol
Patients have begun "swamping" physician offices to ask whether they should end treatment with the cholesterol medication Vytorin, co-marketed by Merck and ...

read more Patients have begun read more Thu Jan 2008 Thu Jan 2008

Vytorin Results Disappointing, Experts Say Don't Panic

Categorie : Cholesterol
The American College of Cardiology (ACC) has issued a statement yesterday, 15th January, asking patients taking the cholesterol busting drugs Zetia (ezetimibe) and Vytorin (ezetimibe and simvastatin combined) not to panic and to talk to their doctors about the impact of the disappointing trial resul ...

read more The American College of Cardiology (ACC) has issued a statement yesterday, 15th January, asking patients taking the cholesterol busting drugs Zetia (ezetimibe) and Vytorin (ezetimibe and simvastatin combined) not to panic and to talk to their doctors about the impact of the disappointing trial resul read more Thu Jan 2008 Thu Jan 2008

Kaiser Daily Health Policy Report Highlights Scrutiny Over Benefit Of Using Statins

Categorie : Cholesterol
Two newspapers on Tuesday reported on scrutiny of statin use and whether the drugs provide prolonged life or benefits to patients with high cholesterol. Summaries appear below.New York Times: In the "fallout from the headline-making ...

read more Two newspapers on Tuesday reported on scrutiny of statin use and whether the drugs provide prolonged life or benefits to patients with high cholesterol. Summaries appear below.New York Times: In the read more Thu Jan 2008 Thu Jan 2008

Phase 1 Studies Show Promise Of QuatRx's Novel Compound, Sobetirome, For Lowering LDL Cholesterol Levels

Categorie : Cholesterol
QuatRx Pharmaceuticals, a privately-held biopharmaceutical company developing compounds for the treatment of major endocrine, metabolic and cardiovascular diseases, announced results from two Phase 1 clinical studies with its novel lipid lowering compound, sobetirome (formerly QRX-431), in develop ...

read more QuatRx Pharmaceuticals, a privately-held biopharmaceutical company developing compounds for the  treatment of major endocrine, metabolic and cardiovascular diseases,  announced results from two Phase 1 clinical studies with its novel lipid lowering compound, sobetirome (formerly QRX-431), in develop read more Thu Jan 2008 Thu Jan 2008

Study Locates Cholesterol Genes; Finds Surprises About Good, Bad Cholesterol

Categorie : Cholesterol
An international study of 20,000 people found seven new genes that influence blood cholesterol levels, a major factor in heart disease, and confirmed 11 other genes previously thought to influence cholesterol. ...

read more An international study of 20,000 people found seven new genes that influence blood cholesterol levels, a major factor in heart disease, and confirmed 11 other genes previously thought to influence cholesterol. read more Tue Jan 2008 Tue Jan 2008

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