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Categorie > Clinical Trials / Drug Trials
EpiCept Announces Encouraging Results Of Phase II Trial For NP-1 Cream In Diabetic Peripheral Neuropathy
Categorie : Clinical Trials / Drug TrialsEpiCept Corporation (Nasdaq and OMX Nordic Exchange: EPCT) today announced preliminary results from its Phase II "Neuracept" trial for EpiCept? NP-1 Cream in patients suffering from diabetic peripheral neuropathy (DPN). All pain scores measured trended in favor of the NP-1 treated patients over the ...
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Tue Feb 2008
Aprotinin And ACE Inhibitors Associated With Postoperative Renal Dysfunction During Off-Pump Cardiac Surgery
Categorie : Clinical Trials / Drug TrialsWhen used during on-pump cardiac surgery, the blood-conserving drugaprotinin appears to be safe. However, when used in combination withangiotensin-converting enzyme (ACE) inhibitors during off-pump cardiacsurgery, it has been associated with a significant risk of renaldysfunction in the postoperativ ...
read more Tue Feb 2008
Data From Anthera's Plasma Trial To Be Presented As Late Breaker At American College Of Cardiology Scientific Sessions
Categorie : Clinical Trials / Drug TrialsAnthera Pharmaceuticals, Inc., a privately held biopharmaceutical company developing anti-inflammatory drugs, announced that data from the Phase II trial of its novel secretory phospholipaseA2 inhibitor Varespladib (A-002) for the treatment of coronary heart disease will be presented as a late brea ...
read more Tue Feb 2008
New 48-Week Efficacy And Safety Data Presented For INTELENCE(TM) (etravirine) As Part Of HIV Combination Therapy
Categorie : Clinical Trials / Drug TrialsNew data showed that at 48 weeks, significantly more treatment-experienced adults with HIV-1 with documented resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs) had an undetectable viral load (defined as less than 50 HIV-1 RNA copies/mL) with INTELEN ...
read more Tue Feb 2008
Ascal Not Safer Than Aspirin
Categorie : Clinical Trials / Drug TrialsChanging prescription of low dose aspirin into calcium carbasalate (brand name: Ascal) to prevent peptic ulcerations is not useful. Peptic ulcers are evenly distributed among users of calcium carbasalate and aspirin, for secondary prevention of myocardial infarction. ...
read more Tue Feb 2008
Hollis-Eden Pharmaceuticals Commences Phase I/II Clinical Trial In Ulcerative Colitis With Novel Oral Anti-Inflammatory Drug Candidate TRIOLEX(TM)
Categorie : Clinical Trials / Drug TrialsHollis-Eden Pharmaceuticals, Inc. (NASDAQ:HEPH), the world leader in the development of a new class of small molecule compounds based on endogenous steroid hormones, announced that it has commenced a Phase I/II clinical trial with its oral drug candidate TRIOLEX? (HE3286) in ulcerative colitis (UC) ...
read more Tue Feb 2008
Positive Results From Phase III Trial Of Gamunex(R) In Patients With CIDP
Categorie : Clinical Trials / Drug TrialsIn the largest trial ever reported in CIDP (chronic inflammatory demyelinating polyradiculoneuropathy), Gamunex® (Immune Globulin Intravenous [Human], 10% Caprylate/Chromatography Purified) was shown to reduce functional disability, while also demonstrating a prolonged time to relapse and a decrease ...
read more Tue Feb 2008
Merck's ISENTRESS® Tablets In Combination With Other Anti HIV Medicines Maintained Reductions In HIV 1 Viral Load And Increased CD4 Cell Counts
Categorie : Clinical Trials / Drug TrialsSENTRESS® (raltegravir) tablets, Merck's HIV integrase inhibitor, in combination with other anti-HIV medicines, maintained significant HIV-1 viral load suppression and increased CD4 cell counts through 48 weeks of therapy compared to placebo in combination with anti-HIV medicines, in two Phase III s ...
read more Tue Feb 2008
Novel Anti-CD20 Monoclonal Antibody Ofatumumab Demonstrates Anti-tumour Responses In Patients With Relapsed/refractory B-cell Chronic Leukaemia
Categorie : Clinical Trials / Drug TrialsData from a Phase I/II study of the novel antiCD20 monoclonal antibody, ofatumumab (formerly HuMax-CD20) in patients with relapsed or refractory B-cell chronic lymphocytic leukaemia (CLL) demonstrate anti-tumour responses in half of the patients treated in one of the three cohorts.[1] The study is p ...
read more Tue Feb 2008
New 48-Week Efficacy And Safety Data Presented For INTELENCE? (Etravirine) As Part Of HIV Combination Therapy
Categorie : Clinical Trials / Drug TrialsNew data showed that at 48 weeks, significantly more treatment-experienced adults with HIV-1 with documented resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors (PIs) had an undetectable viral load (defined as less than 50 HIV-1 RNA copies/mL) with INTELENC ...
read more Tue Feb 2008
CASTLE Study Showed Similar Efficacy Between Once-Daily REYATAZ® (atazanavir Sulfate)/ritonavir And Twice-Daily Lopinavir/ritonavir
Categorie : Clinical Trials / Drug TrialsBristol-Myers Squibb Company (NYSE: BMY) announced results from the CASTLE study, in which 300 mg of once-daily REYATAZ® (atazanavir sulfate) taken with 100 mg of ritonavir (REYATAZ/r) showed similar antiviral efficacy to twice-daily lopinavir 400 mg and ritonavir 100 mg (lopinavir/r) in previously ...
read more Tue Feb 2008
Living Cell Technologies Ltd Company Announcement: Diabetes Trial Supported By US-Based Diabetes Foundation
Categorie : Clinical Trials / Drug TrialsLiving Cell Technologies Limited (ASX: LCT) (PINKSHEETS: LVCLY) announced that the US-based Children with Diabetes Foundation (CWDF), has offered its support in raising funds for LCT's DiabeCell® clinical trials for people with type 1 diabetes. The foundation has established a fund which allows supp ...
read more Tue Feb 2008
Gardasil(R) Demonstrates High Efficacy Against Precancerous Cervical Lesions In Longest Follow-Up Of Large Phase III Clinical Studies
Categorie : Clinical Trials / Drug TrialsA combined analysis of four phase II/III studies which enrolled more than 20,000 women confirmed that the quadrivalent (6,11,16,18) cervical cancer vaccine Gardasil® has sustained 98% to 100% efficacy in the prevention of vaccine virus type-related precancerous cervical lesions in young women. These ...
read more Tue Feb 2008
New IDSA Clinical Practice Guidelines Recommend NOXAFIL(R) (Posaconazole) For Antifungal Prophylaxis In Certain High Risk Patients
Categorie : Clinical Trials / Drug TrialsSchering-Plough Corporation (NYSE: SGP) reported that its antifungal agent NOXAFIL(R) (posaconazole) Oral Suspension received an A-1 recommendation(1) (highest rating) for the prevention of invasive Aspergillus infections in certain high- risk patients in the latest Treatment of Aspergillosis: Cli ...
read more Sun Feb 2008
ADVENTRX To Present ANX-201 Preclinical Data At Keystone Symposia HIV Pathogenesis Conference
Categorie : Clinical Trials / Drug TrialsADVENTRX Pharmaceuticals, Inc. (Amex: ANX), announced that data from preclinical studies of ANX-201, the Company's broad spectrum antiviral product candidate, has been accepted for presentation at the Keystone Symposia HIV Pathogenesis Conference, which takes place March 27-April 1, 2008 in Banff, A ...
read more Sun Feb 2008
M's Science Corporation Initiated European Phase 2 Study In Stroke Recovery
Categorie : Clinical Trials / Drug TrialsM's Science Corporation (MSC), a clinical stage discovery and development company announced that it initiated a Phase 2 study in Europe with its lead product SA4503 for treatment of stroke. Earlier this year, MSC announced the initiation of a Phase 2 trial with SA4503 for the treatment of major depr ...
read more Sun Feb 2008
AVEO Initiates Phase 1b Combination Clinical Trial Of Novel Triple VEGF Receptor Inhibitor AV-951 In Metastatic Renal Cell Carcinoma
Categorie : Clinical Trials / Drug TrialsAVEO Pharmaceuticals, Inc., a biotechnology company leveraging breakthrough discoveries in cancer biology to discover, develop and commercialize targeted oncology therapies, announced that it has initiated a Phase 1b clinical trial for its lead product candidate, the novel triple VEGF receptor inhib ...
read more Sun Feb 2008
African Americans Less Likely To Choose Epidurals For Post Operative Pain Relief
Categorie : Clinical Trials / Drug TrialsMinority and low-income patients are less likely than those who are white or more well off to agree to post-surgery epidural pain relief, according to new research from physicians at the University of Pennsylvania School of Medicine. The study, published recently in the journal Anesthesia and Analge ...
read more Sun Feb 2008
Kiadis Pharma Announces Successful Completion Of Rhitol(TM) Phase II Clinical Study
Categorie : Clinical Trials / Drug TrialsOncology focused biopharmaceutical product development company Kiadis Pharma announced that it has successfully finalized its Rhitol(TM) Phase II clinical trial with the last patient completing its six month treatment cycle. Rhitol(TM) is evaluated as treatment for patients with extensive chronic G ...
read more Sun Feb 2008
MIGENIX To Add 600mg Daily Celgosivir Dose To Phase II Viral Kinetics Study
Categorie : Clinical Trials / Drug TrialsMIGENIX Inc. (TSX: MGI, OTC: MGIFF), a clinical-stage developer of drugs for infectious diseases, will add a 600mg celgosivir combination therapy arm to its currently enrolling Phase II viral kinetics study in hepatitis C virus ("HCV") treatment-naive patients. The protocol amendment to this study ...
read more Sun Feb 2008
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