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Announcing Wide-Ranging ZD4054 Phase III Development Program For Prostate Cancer Treatment

Categorie : Endocrinology
New Phase II data presented suggest that ZD4054, a novel compound in development for the treatment of men with Hormone Resistant Prostate Cancer (HRPC), could offer a promising improvement in overall survival in men with metastatic HRPC who were asymptomatic or mildly symptomatic for pain. Patients ...

read more New Phase II data presented suggest that ZD4054, a novel compound in development for the treatment of men with Hormone Resistant Prostate Cancer (HRPC), could offer a promising improvement in overall survival in men with metastatic HRPC who were asymptomatic or mildly symptomatic for pain. Patients read more Sun Oct 2007 Sun Oct 2007

Sexual Interest Boosted By Hormone Therapy But Not Memory, Study Finds

Categorie : Endocrinology
Hormone therapy in early post-menopause increases sexual interest, but does not improve memory, according to a study in the Sept. 25 issue of the journal Neurology."Contrary to what we predicted, hormone therapy did not have a positive affect on memory performance in younger mid-life women," ...

read more Hormone therapy in early post-menopause increases sexual interest, but does not improve memory, according to a study in the Sept. 25 issue of the journal Neurology. read more Sun Oct 2007 Sun Oct 2007

Role Of 'Flight Or Fight' Hormone Revealed In Mouse Model

Categorie : Endocrinology
Both extensive psychological research and personal experiences confirm that events that happen during heightened states of emotion such as fear, anger and joy are far more memorable than less dramatic occurrences. [click link for full article] ...

read more Both extensive psychological research and personal experiences confirm that events that happen during heightened states of emotion such as fear, anger and joy are far more memorable than less dramatic occurrences. [click link for full article] read more Sun Oct 2007 Sun Oct 2007

FDA Acts To Ensure Thyroid Drugs Don't Lose Potency Before Expiration Date

Categorie : Endocrinology
The U.S. Food and Drug Administration is tightening the potency specifications for levothyroxine sodium, used to treat underactive thyroid glands and other thyroid conditions, to ensure the drug retains its potency over its entire shelf life. This action is being taken in response to concerns that t ...

read more The U.S. Food and Drug Administration is tightening the potency specifications for levothyroxine sodium, used to treat underactive thyroid glands and other thyroid conditions, to ensure the drug retains its potency over its entire shelf life. This action is being taken in response to concerns that t read more Sun Oct 2007 Sun Oct 2007

Safe To Stop The Flow? Differing Attitudes Found Between Women And Doctors Concerning Menstrual Suppression

Categorie : Endocrinology
More than two thirds of women in a national survey say that they are interested in suppressing their menstrual periods but many of them aren't sure if it's safe. Yet when physicians are polled, 97 percent say that continuous oral contraceptive therapy to suppress menstruation is, in fact, medical ...

read more More than two thirds of women in a national survey say that they are interested in suppressing their menstrual periods but many of them aren't sure if it's safe. Yet when physicians are polled, 97 percent say that continuous oral contraceptive therapy to suppress menstruation is, in fact, medical read more Sun Oct 2007 Sun Oct 2007

New Data Reveal Topical Divigel(R) (estradiol Gel) 0.1% Significantly Reduces Frequency And Severity Of Hot Flashes

Categorie : Endocrinology
A study presented at the 2007 Annual Meeting of the North American Menopause Society (NAMS) revealed that Divigel(R) (estradiol gel) 0.1% significantly reduced the frequency and severity of moderate to severe hot flashes associated with menopause. Additional data presented at the meeting found that ...

read more A study presented at the 2007 Annual Meeting of the North American Menopause Society (NAMS) revealed that Divigel(R) (estradiol gel) 0.1% significantly reduced the frequency and severity of moderate to severe hot flashes associated with menopause. Additional data presented at the meeting found that read more Sun Oct 2007 Sun Oct 2007

Wyeth Presents New Phase 3 Data And Updates Regulatory Timing For NDA Filing Of Bazedoxifene/Conjugated Estrogens

Categorie : Endocrinology
Wyeth Pharmaceuticals, a division of Wyeth (NYSE:WYE), presented new data from two Phase 3 studies, which showed that bazedoxifene/conjugated estrogens reduced the number and severity of hot flashes in symptomatic postmenopausal women by up to 80 percent, when compared with placebo. These data, pre ...

read more Wyeth Pharmaceuticals, a division of Wyeth (NYSE:WYE), presented new data from two Phase 3 studies, which showed that bazedoxifene/conjugated estrogens reduced the number and severity of hot flashes in symptomatic postmenopausal women by up to 80 percent, when compared with placebo. These data, pre read more Sun Oct 2007 Sun Oct 2007

Small Papillary Thyroid Cancer Is Not Without Risk

Categorie : Endocrinology
Patients with micropapillary thyroid cancersmall tumors equal to or less than 1 centimeter and tumors even smaller, less than 1 millimeter (mm) are more common and not without a risk as previously thought, according to a new study presented on Fri., Oct. 5, at the 78th Annual Meeting of the American ...

read more Patients with micropapillary thyroid cancersmall tumors equal to or less than 1 centimeter and tumors even smaller, less than 1 millimeter (mm) are more common and not without a risk as previously thought, according to a new study presented on Fri., Oct. 5, at the 78th Annual Meeting of the American read more Sun Oct 2007 Sun Oct 2007

Emotionally Charged Events Leave Their Mark On Memory

Categorie : Endocrinology
Researchers have uncovered new evidence in mice that may explain how emotionally charged situations can leave such a powerful mark on our memories. Surges of the stress hormone norepinephrine (also known as noradrenaline) that often accompany strong emotions spark a series of molecular events that u ...

read more Researchers have uncovered new evidence in mice that may explain how emotionally charged situations can leave such a powerful mark on our memories. Surges of the stress hormone norepinephrine (also known as noradrenaline) that often accompany strong emotions spark a series of molecular events that u read more Sun Oct 2007 Sun Oct 2007

Cause Of Visual Problems Among Children Of Hypothyroid Mothers Found

Categorie : Endocrinology
Children of women with hypothyroidism an under active thyroid who had elevated thyroid stimulating hormone (TSH) in the first and second trimesters of pregnancy, had a significantly reduced ability to see visual contrasts, compared to women with hypothyroidism with normal TSH levels during the first ...

read more Children of women with hypothyroidism an under active thyroid who had elevated thyroid stimulating hormone (TSH) in the first and second trimesters of pregnancy, had a significantly reduced ability to see visual contrasts, compared to women with hypothyroidism with normal TSH levels during the first read more Sun Oct 2007 Sun Oct 2007

Even Mild Thyroid Problems Double Risk Of Heart Conditions

Categorie : Endocrinology
Individuals with subclinical hypothyroidism a mildly underactive thyroid only detectable by a blood test are twice as likely to develop heart failure, compared to those with normal thyroid levels, according to a new study being presented on Thursday, Oct. 4, at the 78th Annual Meeting of the America ...

read more Individuals with subclinical hypothyroidism a mildly underactive thyroid only detectable by a blood test are twice as likely to develop heart failure, compared to those with normal thyroid levels, according to a new study being presented on Thursday, Oct. 4, at the 78th Annual Meeting of the America read more Sun Oct 2007 Sun Oct 2007

Genomic Health Announces Preliminary Results From A Study Of Oncotype DX(TM) In Node-Positive Breast Cancer Patients

Categorie : Endocrinology
Genomic Health, Inc. (Nasdaq: GHDX) announced encouraging results from a study of Oncotype DX in postmenopausal women with node-positive, hormone receptor positive breast cancer conducted by the Southwest Oncology Group (SWOG), a National Cancer Institute clinical trials cooperative group. [cli ...

read more Genomic Health, Inc. (Nasdaq: GHDX) announced encouraging results from a study of Oncotype DX in postmenopausal women with node-positive, hormone receptor positive breast cancer conducted by the Southwest Oncology Group (SWOG), a National Cancer Institute clinical trials cooperative group. [cli read more Sun Oct 2007 Sun Oct 2007

Data Show Vaprisol(R) Is Effective & Safe In Promptly Increasing Serum Sodium Levels In Patients With Euvolemic Or Hypervolemic Hyponatremia

Categorie : Endocrinology
Astellas Pharma US, Inc. announced results of an analysis showing that Vaprisol (conivaptan hydrochloride injection) produced a prompt and sustained (over the 4-day treatment period) increase in serum sodium concentration [Na+] among hospitalized patients with euvolemic and hypervolemic hyponat ...

read more Astellas Pharma US, Inc. announced results of an analysis showing that Vaprisol (conivaptan hydrochloride injection) produced a prompt and sustained (over the 4-day treatment period) increase in serum sodium concentration [Na+] among hospitalized patients with euvolemic and hypervolemic hyponat read more Sun Oct 2007 Sun Oct 2007

Investigating Link Between Male Testosterone Levels And Marital Status

Categorie : Endocrinology
A fascinating new study is the first outside of North America to observe lower testosterone levels among married men. Supporting a growing body of research, the study reveals that even married men who are considered aloof spouses and provide minimal parenting have much lower testosterone levels than ...

read more A fascinating new study is the first outside of North America to observe lower testosterone levels among married men. Supporting a growing body of research, the study reveals that even married men who are considered aloof spouses and provide minimal parenting have much lower testosterone levels than read more Sun Oct 2007 Sun Oct 2007

Hollis-Eden Pharmaceuticals Commencing Phase I/II Clinical Trial With TRIOLEX (HE3286) In Obese, Insulin Resistant Volunteers

Categorie : Endocrinology
Hollis-Eden Pharmaceuticals, Inc. (NASDAQ:HEPH), the world leader in the development of a new class of small molecule compounds based on endogenous steroid hormones, announced that it is commencing this week a two-stage Phase I/II clinical trial with its oral drug candidate TRIOLEX™ ( ...

read more Hollis-Eden Pharmaceuticals, Inc. (NASDAQ:HEPH), the world leader in the development of a new class of small molecule compounds based on endogenous steroid hormones, announced that it is commencing this week a two-stage Phase I/II clinical trial with its oral drug candidate TRIOLEX™ ( read more Sun Oct 2007 Sun Oct 2007

A Person's Height Affects Their Perception of Their Quality Of Life

Categorie : Endocrinology
Your height in adult life significantly affects your quality of life, with short people reporting worse physical and mental health than people of normal height. This large, peer reviewed study, which appears in Clinical Endocrinology, shows that adult height is linked to how good a person thinks the ...

read more Your height in adult life significantly affects your quality of life, with short people reporting worse physical and mental health than people of normal height. This large, peer reviewed study, which appears in Clinical Endocrinology, shows that adult height is linked to how good a person thinks the read more Sun Oct 2007 Sun Oct 2007

Why Some Prostate Cancers Recur After Treatment

Categorie : Endocrinology
Cancer researchers have long worked to understand why some prostate cancers recur after the use of therapies designed to stop the production of testosterone and other androgens that fuel cancer cell growth. New research has now detected that androgen-synthesizing proteins are present within canc ...

read more Cancer researchers have long worked to understand why some prostate cancers recur after the use of therapies designed to stop the production of testosterone and other androgens that fuel cancer cell growth. New research has now detected that androgen-synthesizing proteins are present within canc read more Sun Oct 2007 Sun Oct 2007

Obesity-Related Hormone Is Higher In Children With Down Syndrome

Categorie : Endocrinology
Children with Down syndrome are more likely than their unaffected siblings to have higher levels of a hormone associated with obesity, according to pediatric researchers. The hormone, leptin, may contribute to the known higher risk of obesity among children and adults with Down syndrome. A researc ...

read more Children with Down syndrome are more likely than their unaffected siblings to have higher levels of a hormone associated with obesity, according to pediatric researchers. The hormone, leptin, may contribute to the known higher risk of obesity among children and adults with Down syndrome. A researc read more Sun Oct 2007 Sun Oct 2007

Study Of Living Yeast Cells Sheds Light On A Crucial Signalling Process Also Found In Humans

Categorie : Endocrinology
New insights into the cellular signal chain through which pheromones stimulate mating in yeast have been gained by scientists at the European Molecular Biology Laboratory (EMBL). Similar signal chains are found in humans, where they are involved in many important processes such as the differentiatio ...

read more New insights into the cellular signal chain through which pheromones stimulate mating in yeast have been gained by scientists at the European Molecular Biology Laboratory (EMBL). Similar signal chains are found in humans, where they are involved in many important processes such as the differentiatio read more Sun Oct 2007 Sun Oct 2007

Growth Hormone Applied To Diabetes Wound Healing

Categorie : Endocrinology
Slow or troubled healing processes are one of the many negative outcomes of diabetes and many other human diseases. Diabetes patients not only show deficient tissue healing of sharp wounds but they are also more prone to suffer from chronic wounds, such as ulcers in the lower limbs. [click link for ...

read more Slow or troubled healing processes are one of the many negative outcomes of diabetes and many other human diseases. Diabetes patients not only show deficient tissue healing of sharp wounds but they are also more prone to suffer from chronic wounds, such as ulcers in the lower limbs. [click link for read more Sun Oct 2007 Sun Oct 2007

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