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Categorie > Lupus
La Jolla Pharmaceutical Company Files Marketing Authorization Application For European Regulatory Approval Of Riquent
Categorie : LupusLa Jolla PharmaceuticalCompany (Nasdaq: LJPC) today announced that its Marketing AuthorizationApplication (MAA) has been accepted for review by the European MedicinesAgency (EMEA) for potential approval to market Riquent(R) (abetimussodium), its drug candidate for lupus renal disease, in the Europea ...
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Mon Aug 2006
UT Southwestern Researchers Identify Roles Of Gene Mutations Causing Lupus In Mice
Categorie : LupusIn two related studies, researchers at UT Southwestern Medical Center have pinpointed defective genes in mice responsible for triggering the mysterious autoimmune disease lupus, which prompts the body's immune system to mistakenly attack healthy organs and tissues.A research team led by Dr. [click l ...
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MedImmune Begins Dosing Of Lupus Patients In Phase 1 Clinical Trial
Categorie : LupusMedImmune, Inc.(Nasdaq: MEDI) announced today that it has begun dosing lupus patients in aPhase 1 clinical trial to evaluate the safety and tolerability of MEDI-545,its monoclonal antibody (MAb) targeting interferon-alpha. The MAb is beingdeveloped for the potential treatment of patients with system ...
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Missing Copies Of Important Genes May Increase Risk Of Developing Diseases
Categorie : LupusNew research has found that each person may be missing hundreds of thousands of base pairs or "letters" of the genetic code which can make them more at risk of different diseases. Scientists, studying the disease systemic lupus1, have found that the variation in the number of copies of the same gene ...
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Unexpected Discovery Made By Scientists Exploring Inflammation In Rheumatoid Arthritis
Categorie : LupusBOSTON -- What makes joints in people with rheumatoid arthritis, and related conditions like Lyme disease or lupus, so susceptible to attack by the body's immune system, leading to painful flare-ups and deterioration? The answer may surprise you.The answer did surprise investigators at Joslin Diabet ...
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Anti-malarials Most Effective In Lupus Patients Genetically At Risk Of High Levels Of TNF-alpha
Categorie : LupusAnti-malarial drugs are most effective in people with lupus who are genetically predisposed to high levels of tumour necrosis factor alpha and low levels of the cytokine IL-10. A study published today in the journal Arthritis Research & Therapy reveals that anti-malarial drugs, widely used to treat ...
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Death-resistant T Cells In Female Mice With Lupus
Categorie : LupusProper defense of the body against germs requires the actions of specialized cells of the immune system, known as T cells. Activated T cells must eventually be silenced, or autoimmune diseases such as lupus can result. Researcher Alessandra Pernis and colleagues at Columbia University in New York no ...
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Life-Threatening Lupus Responds To Stem Cell Transplant Therapy
Categorie : LupusTransplanting patients with blood stem cells that originate from their own bone marrow can induce the remission of life-threatening, treatment-resistant lupus, according to a study that took place at Northwestern Memorial Hospital in Chicago. Researchers found that 50 percent of the 50 patients in ...
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Study Demonstrates Safety Of Oral Contraceptives In Women With Lupus
Categorie : LupusIn a major study funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), women with either inactive or stable systemic lupus erythematosus (lupus) - a disease in which the body's immune system mistakenly attac [c ...
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Oral Contraceptives With Estrogen Do Not Worsen Symptoms Of Lupus, Two Studies Say
Categorie : LupusTaking oral contraceptives with estrogen does not exacerbate lupus symptoms in women living with the disease, according to two studies published in the Dec. 15 issue of the New England Journal of Medicine, the Wall Street Journal reports. [click link for full article] ...
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Research published in the NEJM challenges 30-year-old standard of care for lupus patients
Categorie : LupusNew use for immunosuppressive drug offers hope, quality of life to patients. A promising new treatment for lupus challenges the way physicians currently treat patients suffering with lupus kidney disease, according to researchers at the State University of New York (SUNY) Downstate Medical Center. [ ...
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Mycophenolate Mofetil - Clinical trial supports better treatment for lupus nephritis
Categorie : LupusTreating lupus patients suffering from kidney inflammation with a medicine known as mycophenolate mofetil may be more effective in inducing remission than treating them with the standard regimen of intravenous cyclophosphamide (Cytoxan), a new clinical trial indicates. The study, published in Thursd ...
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CellCept® - Statement from Sandra Raymond, President and CEO, Lupus Foundation of America, Inc.
Categorie : Lupus"We applaud the results of a research study on the effectiveness of mycophenolate mofetil (MMF) as a potential new treatment for lupus nephritis (lupus kidney disease) which are published in the November 24, 2005 issue of the New England Journal of Medicine. The multi-center clinical study found tha ...
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Lupus, common anti-seizure drug may help patients
Categorie : LupusA common anti-seizure drug may be effective against certain conditions associated with lupus, according to animal research at Wake Forest University School of Medicine. The drug, valproic acid (Depakote), prevents skin disease and reduces the severity of kidney disease in a mouse model of lupus, sai ...
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Drug may fight lupus and atherosclerosis at the same time
Categorie : LupusPeople with lupus are prone to premature accelerated atherosclerosis. Now scientists at Wake Forest University School of Medicine think they have a way to prevent or decrease this atherosclerosis and prevent heart attacks. "Premature accelerated atherosclerosis is one of the leading causes of death ...
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Resetting epigenetic code could aid lupus patients
Categorie : LupusResearchers at Wake Forest University School of Medicine and the University of Virginia hope to reset part of the "epigenetic code" in lupus patients and thus improve treatment. The epigenetic research focuses on histones, the tiny spools in the nuclei of cells around which DNA winds and compacts wh ...
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Lupus Research Institute awards $4.5 million to advance new science in lupus
Categorie : LupusFollowing an intensive scientific review of the largest number of grant applications ever received--nearly double that of previous years--the national nonprofit Lupus Research Institute (LRI) has awarded $4.5 million in new grants to 15 scientists investigating highly promising novel research approa ...
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Lupus - key cellular checkpoint found
Categorie : LupusBy snipping out and analyzing tiny samples of patients' tonsils, scientists have identified a key cellular checkpoint that is somehow bypassed in lupus patients, where harmful immune cells that normally are squelched by the body are mistakenly granted access. [click link for full article] ...
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Study Suggests Plastics Ingredient Triggers Lupus
Categorie : LupusOn the heels of research linking a common chemical compound to reproductive abnormalities in humans, an Indiana State University studyhas found a connection between the same chemical and an auto-immune disease that shortens the life-span of mice. Recent research at the University of Rochester School ...
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