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Crammed With Charged DNA, Pressure Rises Inside Virus
Genetics It could be an artist's depiction of someone's stomach before and after a rather decadent meal. But it is a 3-D cryoelectron microscope reconstruction of the cross-section of a virus, before and after cramming itself full of its own DNA. The virus, phi29, has a tiny motor that pumps its DNA into the capsid-outer shell-during the assembly process. The potential energy of the tightly coiled DNA may help phi29 inject its genetic material into the bacterial cells it infects. [click link for full article]
