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IUGR- Intrauterine Growth Retardation
Pregnancy
Definition:
A fetus whose estimated weight is below the 10th percentile for its
gestational age and whose abdominal circumference is below the 2.5th percentile.
At term, the cutoff birth weight for IUGR is 2,500 g (5 lb, 8 oz).
» COLLEEN M. KENNEDY, M.D.,
and STEPHEN K. HUNTER, M.D., PH.D.
» University of Iowa Hospitals and Clinics, Iowa City, Iowa
Neonatal Classification:
• Small for gestation age (< 10th percentile)
• Appropriate for gestation age
• ( 10th – 90th percentile)
• Large for gestation age ( > 90th percentile)
Value of Diagnosing IUGR:
• 15-fold increased risk of still birth
• Increased risk of cesarean section for fetal distress, increased risk of neonatal resuscitation
• Increased risk of respiratory distress, intra- ventricular hemorrhage and neonatal mortality
• Impaired neurodevelopment at later life.
Types of IUGR:
Symmetrical: (IMPAIRED INTRAUTERINE GROWTH POTENTIAL OF FETUS). CHROMOSOMAL DEFECTS , VIRAL INFECTIONS.
Asymmetrical: UTERO-PLACENTAL INSUFFECIENCY.
Factors Responsible for IUGR:
Fetal Factors:
Infection
Heart disease
Chromosomal Malformations
Osteogenesis imperfecta
Maternal Factors:
Cardio-respiratory disease
Renal disease
Acidosis
Anemia/ fever
Drugs & Alcohol
Smoking
Uterine Factors:
Reduced uteroplacental flow
Arteriosclerosis
Connective tissue disorders
Ch HTN
Pre eclampsia
Diabetes
Fibromyoma
Placental Factors:
Placenta previa
Thrombosis/ infarction
Deciduitis
Placentitis/ vasculitis
Chorioamnionitis
Placental cysts/ chorioangioma
