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Colon Cancer Gene Reveals New Function
Colorectal Cancer Dartmouth Medical School geneticists have discovered a striking turnabout role for a gatekeeper known to put on the brakes for colon cancer. Flaws in a gene called adenomatous polyposis coli (APC), which normally prevents excessive cell growth, are thought to trigger development of most colorectal cancers.But in an about face, the tumor suppressor gene also has a second task, the researchers found, as a gas pedal that accelerates signaling between cells.
