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Calixa Therapeutics Announces Positive Phase 1 Results For CXA-101, A Novel Intravenous Cephalosporin Antibiotic
Infectious Diseases / Bacteria / Viruses Calixa Therapeutics Inc. announced positive results from a Phase 1 trial of intravenous CXA-101, a novel cephalosporin antibiotic with excellent in vitro anti-pseudomonal activity. The results from this first Phase 1 study demonstrated that CXA-101 was well tolerated, with a clinical and laboratory safety profile similar to that of marketed cephalosporin antibiotics. No dose-limiting toxicity was observed, even at the highest dose regimen evaluated.